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CRISPR study reveals new immune system regulators

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Scientists have created the first retroviral CRISPR-Cas9 gene editing library to explore the regulation of mouse T cells, which are key cells in the immune system. Researchers from the Wellcome Sanger Institute and their collaborators mapped the most important genes for controlling T helper cells, and identified several new regulatory genes. Published in Cell, these could help researchers develop new treatments to activate the immune system against tumours or infection.

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